Andrographolide 98% Chinese Herbal Extract Health For Medic

Andrographolide 98% Chinese Herbal Extract Health For Medicine

Quick Detail:

1.Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.

2. Andrographolide is an extremely bitter substance extracted from the stem and leaves of A. paniculata.

3.Andrographolide is used experimentally in different areas of research including cell signaling, immunomodulation, and stroke

Detailed Description:

Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Andrographolide is an extremely bitter substance extracted from the stem and leaves of A. paniculata.

Andrographolide is used experimentally in different areas of research including cell signaling, immunomodulation, and stroke.

While Andrographolide is a relatively simple diterpene lactone, the biosynthesis by Andrographis paniculata was only recently determined. Andrographolide is a member of the isoprenoid family of natural products. The precursors to isoprenoid biosynthesis, isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP), can be synthesized through either the Mevalonic Acid (MVA) or deoxyxylulose (DXP) pathway. Through selective C13 labeling of the precursors to both the MVA and DXP pathways, it was determined that the majority of the Andrographolide precursors are synthesized through the DXP pathway. It is worth noting that there is still a small portion of Andrographolide precursors are synthesized through the MVA pathway. The biosynthesis of Andrographolide begins with the addition of IPP to DMAPP, which forms GPP. Another molecule of IPP is then added, yielding FPP. The final IPP molecule is added to the FPP to complete the backbone of the diterpene. The double bond originating from DMAPP is oxidized to an epoxide prior to the ring closing cascade that forms two six-membered rings. A series of oxidations form a five-membered lactone in addition to adding on the alcohol groups. The order of these post-synthetic modifications is not entirely known.

Specifications:

Applications:

1.Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Andrographolide is an extremely bitter substance extracted from the stem and leaves of A. paniculata.

2.Andrographolide is used experimentally in different areas of research including cell signaling, immunomodulation, and stroke.

3.While Andrographolide is a relatively simple diterpene lactone, the biosynthesis by Andrographis paniculata was only recently determined. Andrographolide is a member of the isoprenoid family of natural products. The precursors to isoprenoid biosynthesis, isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP), can be synthesized through either the Mevalonic Acid (MVA) or deoxyxylulose (DXP) pathway. Through selective C13 labeling of the precursors to both the MVA and DXP pathways, it was determined that the majority of the Andrographolide precursors are synthesized through the DXP pathway. It is worth noting that there is still a small portion of Andrographolide precursors are synthesized through the MVA pathway. The biosynthesis of Andrographolide begins with the addition of IPP to DMAPP, which forms GPP. Another molecule of IPP is then added, yielding FPP. The final IPP molecule is added to the FPP to complete the backbone of the diterpene. The double bond originating from DMAPP is oxidized to an epoxide prior to the ring closing cascade that forms two six-membered rings. A series of oxidations form a five-membered lactone in addition to adding on the alcohol groups. The order of these post-synthetic modifications is not entirely known.

Competitive Advantage:

We have Andrographis paniculata (Burm. f.) Nees about 2000 acre in ningxia province.so the materials of goji juice is from our farm.that means we have the lowest cost of materials and our goji juice have competitive price.just send me an enquiry and we can prove it.