Helicobacter Pylori (HP)Antigen Rapid Test

Helicobacter Pylori INTENDED USE
The Helicobacter-Pylori antigen rapid test kit (stool) is a rapid visual immunoassay for the qualitative detection of
helicobacter pylori antigen in human stool specimens. This kit is used as an aid in the diagnosis of H. pylori
infection.

Helicobacter Pylori INTRODUCTION
Helicobacter pylori (also known as Campylobacter pylori) as a spiral-shaped gram negative bacteria which infects the
gastric mucosa. H. pylori to causes several gastro-enteric diseases such as non-ulcerous dyspepsia, gastric and
duodenal ulcer, active gastritis and can even increase the risk of stomach adenocarcinoma.
The epidemiologic study shows that more than 50% of the world's population is infected by H. pylori strains. Infection
is more prevalent in developing countries. The lowest infection rate is 20%, and the highest infection rate can be 90%
in developing countries. H. pylori strains is the major reason to cause chronic gastritis and gastric ulcers, 80%-90%
chronic gastritis patients and 95%-100% gastric ulcers patients are infected by H. pylori strains. So the detection and
treatment of H. pylori strains infection is very important.
At present several invasive and non-invasive approaches are available to detect this infection state. Invasive
methodologies require endoscopy of the gastric mucosa with histologic, cultural and urease investigation, which are
expensive and require some time for diagnosis. Alternatively,non-invasive methods are available such as breath tests,
which are extremely complicated and not highly selective, and classical ELISA and immunoblot assays. This Kit
belongs to non-invasive approach.